Abstract
<jats:p>Cities in the global context experience a series of isomorphisms related to the matter and energy required for the functioning and operation of various intrasystemic processes—that is, understanding the city as a thermodynamic system. In this sense, urban homogeneities are often identified through climatic manifestations, with repercussions and concerns in areas such as water resources, sanitation, mobility, and other forms of entropy such as economic, sociocultural, educational, or security-related. This contribution reflects on the current state of cities immersed in increasingly uncertain and complex scenarios. To that end, a review of 50 thematic sources was conducted, and from a systemic perspective, the conceptual model known as Entropy–Homeostasis–Negentropy (EHN) was analyzed in terms of its scope, limitations, and relevance for urban studies. The review of various bibliographic sources that have adopted this theoretical framework may offer new insights and research lines, even extending into studies in other disciplines. In the case of the EHN model, the boundaries between each phase are not clearly defined, suggesting that future developments and research could move beyond purely qualitative interpretations toward quantitative delimitations of broader interest.</jats:p>