Omega-3 Fatty Acids for Anxiety: Patient Selection, EPA-to-DHA Ratio, Dosing, and AFib Risk

<jats:p>Omega-3s offer anti-inflammatory effects and potential anxiolytic benefits. In clinical practice, consider them for anxious patients who are overweight, have high triglycerides, or hs-CRP above 3. Start omega-3s at 1 gram daily of a third-party-tested formula with an EPA-to-DHA ratio of 3:2. Target 2 grams daily after one week if no side effects appear. Discontinue omega-3 ethyl esters permanently if atrial fibrillation develops. Risk is dose-dependent, and highest at 4 grams daily.</jats:p>