Back to Search View Original Cite This Article

Abstract

<jats:p>Behcet’s disease is an occlusive vasculitis of unknown etiology affecting multiple organ systems. Ocular Behcet’s disease occurs in about 70% of patients, of which up to 25% can lead to vision loss due to developing uveitis. Corticosteroids, immunomodulators, antimetabolites, and biological drugs are used to treat Behcet’s disease, the long-term use of which can lead to the development of numerous serious complications (infections (viral, bacterial, fungal)). A female patient, who has been receiving outpatient care at the Eye Center after S.V. Malayan since 2012, developed both viral (acute retinal necrosis) and fungal (fungal endophthalmitis) infection as a result of long-term use of immunosuppressants (prednisolone, azathioprine (Imuran), cyclosporine). For treatment, the necrosis zone was limited by laser photocoagulation and fungal endophthalmitis treatment was prescribed (amphotericin, fluconazole, nonsteroidal anti-inflammatory eye drops, and itraconazole tablets). No recurrence of the infectious process has been observed. The patient’s condition is satisfactory. Therefore, we can note that drug treatment of Behcet’s disease can lead to immunosuppression and, consequently, the development of an infectious process, which, in turn, can lead to loss of visual acuity and even of the visual organ. Therefore, timely and correct diagnosis and treatment are extremely important.</jats:p>

Show More

Keywords

behcets disease lead fungal treatment

Related Articles