Abstract
<jats:p>This study addresses key issues highlighting the detrimental role of calcium in the pathogenesis of Parkinson’s Disease (PD), the importance of regulating systems of it, and new suggestions for the prevention and management of PD. It is well known that the most effective way to combat any disease is through etiopathogenetic treatment, and calcium ion imbalance is considered one of the causal factors of PD. This raises the idea that if there is a need to correct calcium homeostasis, then there is also a need to investigate and to control the calcium regulatory systems. Since there are currently few studies clarifying the role of these systems in the pathogenesis of PD, this research is highly relevant and shows that homeostatic corrections in these systems could become new and more effective approaches for both early prevention and therapeutic treatment of the disease.</jats:p>