Prevention of stress ulcers of the upper gastrointestinal tract. Methodological recommendations of the All-Russian public organization “Federation of Anesthesiologists and Reanimatologists”, Профилактика стресс-язв верхних отделов желудочно-кишечного тракта. Методические рекомендации Общероссийской общественной организации «Федерация анестезиологов и реаниматологов»

<jats:p>In critically ill patients systemic hypoperfusion can lead to gastrointestinal (GI) mucosal injury, predisposing patients to clinically significant or non-significant bleeding. Bleeding from stress ulcers leads to prolonged intensive care unit (ICU) stays and an increased risk of negative clinical outcomes. A wide range of potential risk factors (prolonged mechanical respiratory support, sepsis, traumatic brain and spinal injury, severe burns, coagulopathy, ulcer history, etc.) leads to the indiscriminate use of pharmacological agents and to the wide routine administration of antisecretory drugs in more than 80–85 % of critically ill patients. The guidelines present the basic principles of upper gastrointestinal stress ulcer prophylaxis in intensive care patients.</jats:p>