Abstract
<title>Abstract</title> <p> <bold>The aim of this study</bold> : to identify factors predicting perforation during colorectal stenting of tumour strictures. <bold>Materials and methods</bold> : This study involved a retrospective analysis of 314 patients with acute obstructive intestinal obstruction caused by colorectal cancer who underwent stenting of tumour strictures. The main parameters for evaluation were: determination of technical success and clinical efficacy, mortality rate, frequency of complications, and factors predisposing to perforation during stenting. <bold>Results</bold> : Technical success in colorectal stenting was achieved in 98% of cases (308 patients). Clinical success was 89% (282 patients). Complications following stenting were observed in 30 patients (9.5%): colon perforation – 18 patients (5.7%), stent migration – 8 patients (2.5%), bleeding – 4 patients (1.3%). According to univariate and multivariate logistic regression analysis: tumour location at a physiological curve, total colonic obstruction (lumen diameter ≤ 2 mm), the presence of diverticula at the stent placement site, stage IV of the tumor process, carcinomatosis and dilatation of the tumour stricture prior to colon stenting were significant independent prognostic factors for the development of complications (colonic perforation). <bold>Conclusions.</bold> Colorectal stenting for acute intestinal obstruction is an effective and safe treatment method, demonstrating high rates of both technical and clinical success. A long tumour stricture is a prognostic factor indicating lower rates of clinical success. Predictors of colonic perforation during colorectal stenting include: tumour location in the area of a physiological curve; complete colonic obstruction (lumen diameter ≤ 2 mm); the presence of diverticula in the area where the stent is placed; stage IV of the tumor process; carcinomatosis and dilatation of the tumour stricture prior to stenting. </p>