Abstract
<jats:p>Computer models and protocols commonly used for superficial thermotherapy assume anatomically symmetric tissue geometries. However, anatomical variability, particularly the variability of the adipose tissue thickness may have a significant impact on heat transfer and cause non-uniform thermal doses in the patient population. This paper studies the influence of anatomical asymmetry due to adipose tissue thickness on heat propagation during superficial thermotherapy based on combined computational and experimental analyses. A Finite Element Model of the lower limb was designed with anatomically representative layers and tissue thermal properties. Parametric simulations were conducted for medium (M) and extra-large (XL) models at hot-pack temperatures (38–44 °C) for 15 min. The simulation results were verified experimentally on ex vivo porcine tissue. The results showed that the thickness of adipose tissue significantly affected deep-tissue heating. When the same heating condition was applied, the boundary temperature of the muscle was increased by ~1.03 °C for the 44 °C hot-pack in the M-size model and was restricted to 0.21 °C for the XL-size model. The experimental measurements indicated an increase of 1.16 °C in the muscle temperature, with an average difference of 0.81 °C between numerical predictions and experimental measurements. These results show that anatomical asymmetry has a strong effect on heat transfer during superficial thermotherapy and challenge the precept that standard heating protocols provide similar thermal doses in different body morphologies.</jats:p>